3-(1-(Dimethylamino)ethyl]phenol

Hoʻohana ʻia ʻo 3-(1-(Dimethylamino)ethyl]phenol ma ke ʻano he waena o Rivastigmine tartrate.
ʻO Rivastigmine tartrate ka rivastigmine nā lāʻau maʻi o Alzheimer, ʻo rivastigmine ka physostigmine derivative e Novartis no ka manawa mua i hoʻomohala maikaʻi i ka inoa kalepa ʻo Exelon (exelon), kahi mole me ka hana carbamate ma laila, he ʻano amino acid o ka koho cerebral cholinesterase inhibitor, hiki ke pale aku. ʻO ka acetylcholinesterase a me ka butyrylcholinesterase, nā neurons cholinergic ma ka hoʻopaneʻe ʻana i ka hoʻokuʻu ʻana o ka acetylcholine degradation a me ka ikaika e hāpai ana i ka conduction nerve cholinergic, hiki ke hoʻomaikaʻi i nā maʻi hana cognitive i hoʻopili ʻia e cholinergic, a laila e hoʻomaikaʻi ai i ka hana cognitive o nā maʻi maʻi o Alzheimer.He nāwaliwali ka hoʻopaʻa ʻana o ka protein plasma Rivastigmine, maʻalahi ma o ka pale koko-lolo, kahi kiʻekiʻe o ka koho lolo.ʻAʻole wale ia e hana maʻalahi i ka cerebral cortex a me ka hippocampus i maʻalahi loa, akā makemake pū kekahi i ka subtype dominant o AChE i loko o ka lolo, e hoʻemi ana i ka maikaʻi o nā hopena ʻaoʻao cholinergic peripheral.ʻO ka Rivastigmine i loko o vivo ka hapalua o ke ola he pōkole a lōʻihi ka lōʻihi o ka hana.ʻAʻole like me ka tacrine, ʻoi aku ka ikaika o kēia huahana i ka hippocampus a me ka cortex o ka hopena inhibitory enzyme G1.Ke kauka no ka mālama ʻana i ke ʻano dementia ʻano haʻahaʻa a me ka haʻahaʻa, a i ʻole ka maʻi Alzheimer hiki ke hoʻopaʻapaʻa ʻia ʻo ia ka maʻi o Alzheimer.