Hoʻolaʻa ʻia i ka mana koʻikoʻi a me ka ʻoihana mea kūʻai noʻonoʻo, loaʻa pinepine kā mākou mau limahana limahana e kūkākūkā i kāu mau koi a hana i kahi leʻaleʻa kūʻai piha piha no ka High definition Supply 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' mākaukau e hui pū me nā hoaaloha maikaʻi o ka ʻoihana mai kou hale a i waho a hana i kahi manawa lōʻihi maikaʻi loa.
Hoʻolaʻa ʻia i ka mana maikaʻi loa a me ka ʻoihana kūʻai noʻonoʻo, ʻike pinepine kā mākou mau limahana limahana e kūkākūkā i kāu mau koi a hauʻoli i ka mea kūʻai aku.Kina Imidazole a me Imz, I kēlā me kēia makahiki, nui nā mea kūʻai aku e kipa i kā mākou hui a loaʻa i nā holomua ʻoihana nui e hana pū me mākou.Hoʻokipa maikaʻi mākou iā ʻoe e kipa mai iā mākou i kēlā me kēia manawa a hui pū mākou e lanakila i ka lanakila nui ma ka ʻoihana lauoho.
ʻO ka waena no ka synthesis o allopurinol.
ʻO ia kekahi o ka 3-amino-4-substituted pyrazole series.Hiki ke hoʻohana ʻia ma ke ʻano he mea waena e synthesize i nā mea hoʻohui lāʻau lapaʻau maikaʻi loa, e like me allopurinol, kekahi o ka pyrazolopyrimidine derivatives series, ka mea hope mai 1963 Mai kona hoʻohana ʻana i ka lāʻau lapaʻau, ʻo ia ka lāʻau nui no ka mālama ʻana i ka gout.I kēia manawa, liʻiliʻi nā ala i ʻike ʻia no ka synthesizing
ʻO ka 3-aminopyrazole-4-carboxamide hemisulfate ma Kina, ma ka hana ʻana i ka malononitrile a me ka triethyl orthoformate e hoʻomākaukau ai i ka ethoxymethylene malononitrile, a laila me ka hopena o ka hydrazine hydrate e hāʻawi mai i ka 3-amino-4-cyanopyrazole, ka mea i hoʻopau hope ʻia me ka acidic concentrated.
3-aminopyrazole-4-carboxamide hemisulfate (Chen Huiru, Xiao Guomin et al. 3-aminopyrazole- Synthesis o 4-formamide hemisulfate [J]. Chemical Industry Times, 2008, 6 (22): 39 40), ka huina o ka hua o ʻO ka synthesis ma kēia ala e pili ana i 60% (helu ʻia e like me ka malononitrile), ʻo kēia ʻano hana ʻekolu mau ʻanuʻu, ʻoi aku ka lōʻihi o nā ʻanuʻu, a ʻo nā reagents i hoʻohana ʻia, e like me malononitrile a me ethoxymethylene malononitrile, ʻoi aku ka ʻona a me ke kumukūʻai.Eia kekahi,ʻo ka 3-aminopyrazole-4 i hoʻomākaukauʻia e kēiaʻano -Formamide hemisulfate he kala paʻakikī e wehe a koi aku i ka hana hou,ʻoi aku ka paʻakikī.
Aia nā hōʻike ma nā palapala haole e hoʻohana ana i ka pyridylamide hydrazone a me ka ethoxymethylene malononitrile ma ke ʻano he kumu waiwai e loaʻa ai ka 3-amino-4-cyanopyrazole ma o ka hoʻohui ʻana a me ka cyclization, a laila e hana me ka sulfuric acid concentrated e loaʻa ai ka pūhui pahuhopu (Reuken G Jones. Reactions of orthoesters with pūhui activemethylene[J] J Am Chem Soc. 1952,74(5) :4889 4891).ʻO nā kumu waiwai nui i hoʻohana ʻia i kēia ʻano he kumukūʻai, ʻaʻole kiʻekiʻe ka hopena o ka hopena, a haʻahaʻa ka loaʻa kālā o ka hana ʻoihana.Paʻakikī paha.
Kūlana hoʻokō:Kūlana ʻoihana
waho:ʻO ka pauka keʻokeʻo a melemele paha
Pūʻolo:25kg / pahu
hōʻike (HPLC) ʻoi aku ka nui a i ʻole like me 98.0%
ʻoi aku ka maʻemaʻe (HPLC) ma mua o 99.5% a i ʻole like.
Hoʻolaʻa ʻia i ka mana koʻikoʻi a me ka ʻoihana mea kūʻai noʻonoʻo, loaʻa pinepine kā mākou mau limahana limahana e kūkākūkā i kāu mau koi a hana i kahi leʻaleʻa kūʻai piha piha no ka High definition Supply 99% Imidazole/1h-Imidazole/Imz CAS 288-32-4, We' mākaukau e hui pū me nā hoaaloha maikaʻi o ka ʻoihana mai kou hale a i waho a hana i kahi manawa lōʻihi maikaʻi loa.
ʻO ka wehewehe kiʻekiʻeKina Imidazole a me Imz, I kēlā me kēia makahiki, nui nā mea kūʻai aku e kipa i kā mākou hui a loaʻa i nā holomua ʻoihana nui e hana pū me mākou.Hoʻokipa maikaʻi mākou iā ʻoe e kipa mai iā mākou i kēlā me kēia manawa a hui pū mākou e lanakila i ka lanakila nui ma ka ʻoihana lauoho.