Rivaroxaban（S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban（S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Hoʻohana ʻia i nā poʻe maʻi maʻi me ka ʻoki ʻoki ʻāʻī a i ʻole ke kuli e pale ai i ka thrombosis venous (VTE).
Hoʻohana ʻia ia e pale a hōʻemi paha i ka hoʻokumu ʻia ʻana o ka thrombosis, deep vein thrombosis (DVT) a me ka pulmonary embolism (PE) ma hope o ke kaʻe ʻana o ka ʻūhā a i ʻole ke kuli.
ʻO ka maʻa i ʻōlelo ʻia he rivaroxaban waha 10mg, hoʻokahi manawa i ka lā.Hiki ke lawe ʻia ʻo Rivaroxaban 10mg me ka meaʻai a i ʻole.Pono e lawe ʻia nā papa Rivaroxaban 15mg a i ʻole 20mg me ka meaʻai.
maʻamau: usp40
ʻIke: 99-102%
ʻO waho: ka pauka keʻokeʻo
Pākē: 25kg / pahu
E lawe i ka 4-(4-aminophenyl) morpholin-3-one (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) ka mea hoʻomaka. .Ma hope o ka condensation, cyclization, aminolysis a me ka acylation, loaʻa ka rivaroxaban crude, a hoʻomaʻemaʻe ʻia ka rivaroxaban i hoʻopau ʻia.
Hoʻomākaukau: He papa ʻulaʻula kēia huahana i uhi ʻia.
Nā mea komo:
Papa papa: microcrystalline cellulose, croscarmellose sodium, lactose monohydrate, hypromellose, sodium lauryl sulfate, magnesium stearate
Ka uhi: polyethylene glycol, hypromellose, titanium dioxide, ʻulaʻula hao hao
ʻO Rivaroxaban kahi lāʻau lapaʻau koho nui loa e hoʻopaʻa pono i ka factor Xa.Ma o ka hoʻopaʻapaʻa koho nui a me ka hoʻokūkū hoʻokūkū o ka mea Xa manuahi a me ka hana prothrombin, e hoʻolōʻihi i ka ʻāpana thromboplastin time plate (PT) a me ka prothrombin time (aPTT) ma ke ʻano i hilinaʻi ʻia, hiki ke hoʻopau i ka wailele coagulation ʻO nā ala endogenous a exogenous. pale i ka hana o ka thrombin a me ka thrombosis.ʻAʻole ʻae ʻo Rivaroxaban i ka thrombin (activating factor Ⅱ), ʻaʻole hoʻi i hōʻoia i ka hopena i nā platelets.
ʻO ka ʻokoʻa koʻikoʻi ma waena o rivaroxaban a me fondaparinux/heparin ʻaʻole ia e koi i ke komo ʻana o ka antithrombin III a hiki ke kūʻē pololei i ka mea manuahi a paʻa Xa;ʻoiai ʻo ka heparin e koi ana i ka antithrombin III e hana, a ʻaʻohe hopena i ka mea Xa i loko o ka prothrombin complex.
Ua loaʻa iā JIN DUN MedicalʻO ka hōʻailona ISO a hoʻokō i nā kūlana hana GMP, hoʻohana i nā loea hoʻolaʻa lāʻau kūloko a me nā haole me ka ʻike waiwai e alakaʻi i ka R&D o ka hui.
NA POMAIKAI ANA IA
●Kiʻekiʻe Pressure Catalytic Hydrogenation.ʻO ke kiʻekiʻe o ka Hydrogenolysis Reaction.Cryogenic Reaction (<-78%C)
●Aromatic Heterocyclic Synthesis
● Hoʻoponopono hou
●Chiral Resolution
●Heck, Suzuki, Negishi, Sonogashira .Pane ʻo Gignard
Mea lako
Loaʻa i kā mākou Lab nā mea hoʻokolohua like ʻole, e like me: NMR (Bruker 400M) 、HPLC, chiral-HPLC, LC-MS, LC-MS/MS (API 4000)、IR, UV, GC, GC-MS, Chromatography, ʻO ka Microwave Synthesizer, Parallel Synthesizer, Differential Scanning Calorimeter (DSC), Electron Microscope...
Pūʻulu R&D
He pūʻulu o nā limahana R&D ʻoihana ʻo Jindun Medical, a hoʻohana i nā loea synthesis lāʻau kūloko a me nā ʻāina ʻē e alakaʻi i ka R&D, e ʻoi aku ka pololei a me ka maikaʻi o kā mākou synthesis.
Ua kōkua mākou i kekahi mau ʻoihana lapaʻau kūloko kiʻekiʻe, e like meHansoh, Hengrui a me HEC Pharm.Maanei e hōʻike mākou i kahi hapa o lākou.
Hana Hana Hoʻokahi:
Ka helu helu: 110351-94-5
Hana Hana Hana ʻelua:
Ka helu helu: 144848-24-8
Hana Hoʻoponopono ʻEkolu:
Ka helu helu: 200636-54-0
1.Hoʻopilikino i nā mea waena hou a i ʻole API.E like me ka mea ma luna o ka hihia kaʻana like, nā mea kūʻai aku i nā koi no nā Intermediates kūikawā a i ʻole API, a ʻaʻole hiki iā lākou ke ʻike i nā huahana e pono ai i ka mākeke, a laila hiki iā mākou ke kōkua iā Customize.
2.Hoʻoponopono Kaʻina no nā Huahana Kahiko.E kōkua kā mākou hui i ka Optimize a hoʻomaikaʻi i ka hana ʻana i ke ala ʻoi aku ka wā kahiko, kiʻekiʻe ke kumu kūʻai, a haʻahaʻa ka hana.Hiki iā mākou ke hāʻawi i nā palapala piha no ka hoʻololi ʻenehana a me ka hoʻomaikaʻi ʻana i ke kaʻina hana, kōkua i ka mea kūʻai aku no ka hana ʻoi aku ka maikaʻi.
Mai nā pahuhopu lāʻau i nā IND, hāʻawi ʻo JIN DUN Medical iā ʻoenā hoʻonā R&D pilikino hoʻokahi.
Ke koi nei ʻo JIN DUN Medical i ka hoʻokumu ʻana i kahi hui me nā moeʻuhane, hana i nā huahana hanohano, meticulous, rigorous, a hele i nā mea a pau e lilo i hoa hilinaʻi a me ka hoaaloha o nā mea kūʻai aku!
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