Guanosine

Hoʻohana ʻia ʻo Guanosine ma ke ʻano he waena o Valaciclovir.
ʻO Valacyclovir kahi lāʻau antiviral analogue guanine.Hoʻohana ʻia ia i ka lāʻau lapaʻau o ka herpes simplex a me ka maʻi herpes zoster i nā maʻi i lawe ʻia e ka wahine.ʻO kēia huahana ka mea mua o ka acyclovir.Hoʻopili koke ʻia ia ma hope o ka lawelawe waha a hoʻololi koke ʻia i acyclovir i ke kino.Hoʻokani ʻia kona hopena antiviral e acyclovir.Ma hope o ke komo ʻana o ka acyclovir i nā sela maʻi herpes, hoʻokūkū ʻo ia me ka deoxynucleoside no ka thymidine deoxynucleoside kinase a i ʻole cell kinase, a ua phosphorylated ka lāʻau i loko o ka acyclic guanosine triphosphate.Ma ke ʻano he substrate o ka replication virus, hoʻokūkū ʻo acyclovir me ka deoxyguanine triphosphate no ka maʻi DNA polymerase, ka mea e pale ai i ka synthesis DNA virus a hōʻike i ka hopena antiviral.ʻOi aku ka maikaʻi o ka hana antiviral o kēia huahana i loko o ka vivo ma mua o ka acyclovir, a ʻo ka papa kuhikuhi mālama o ka herpes simplex virus type I a me type II he 42.91% a me 30.13% kiʻekiʻe ma mua o ka acyclovir.Loaʻa iā ia ka hopena curative kiʻekiʻe i ka maʻi varicella zoster.